While Spinach aptamers are the most prevalent, our current research focuses on determining an efficient way to connect Mango aptamers with another aptamer to create a biosensor and to work out an effective method to separate out sequences that bind to TO1-Biotin. So why bother with Mango? Read and find out! Spinach Aptamer The Spinach... Continue Reading →
Aptamers can be used for various applications, including medical diagnostics, molecular sensors and switches etc. But what about therapeutics? In this blog, I want to give an insight on my project that is aiming to use an aptamer as a therapeutic tool against familial Amyotrophic Lateral Sclerosis. First off, What is Amyotrophic Lateral Sclerosis (ALS) and... Continue Reading →
Aptamers are not considered a conventional technique. Aptamer selection technology was developed about a quarter of a century ago. In the beginning, aptamers were immediately thought to be a revolutionary start into solving many problems associated with the diagnostics and the therapy of diseases. However, multiple attempts to use aptamers in practice generally have been less... Continue Reading →
Possible applications for aptamer use are a big part our research here in the Aptamer Stream at UT Austin! Our students get to develop their own applications and do research on literature as to how this aptamer can be developed, all while attempting to find that aptamer via the SELEX process in lab. Some of... Continue Reading →
This past summer, we were very fortunate to participate in the FIRE Summer Fellowship Program. We worked with six other rising sophomores and our Research Educator, Dr. Spirito, on continuing our projects from the spring. Our project focused on using the SELEX process to find RNA molecules that bind strongly to a target protein. We... Continue Reading →
Welcome to Our Lab Hello everyone, this is Chih Hao Wu and Anuj Apte from the University of Maryland! The FIRE (First Year Innovation and Research Experience) Engineering Biosensors group is a new research stream here at the University of Maryland and we already have 6 aptamer-related projects in the making. Here on this post, Anuj... Continue Reading →
Aptamers and Biosensors 